MAPS:
A database and an interactive Webserver of Membrane Annotated Protein
Structures
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Although membrane annotation is essential for
understanding the functions and subtleties of structures of
transmembrane (TM) proteins, the explicit position of membranes in TM
proteins is absent in the pdb. Using a simple hydrophobic
lipid-protein mismatch energy and a flexible lipid/water boundary, we
have annotated the position of lipid bilayer for all TM proteins in
pdb. One can either access the Membrane Annotated Protein Structure
(MAPS) database or interactively analyze membrane-protein
orientations of any uploaded pdb structure. Publication: Jitender Cheema and Gautam Basu(2011) MAPS: An interactive webserver for memebrane annotation of transmembrane protein structures, Ind. Journal of Biochemistry & Biophysics, vol 48, pp. 106-110 [PDF version : Link] |
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