Joyoti Basu
Senior Professor,  Chemistry

List of  publications 

Dasgupta, A., Sureka, K., Mitra, D.,  Saha, B., Sanyal, S.,  Das,  A.K., Chakrabarti, P., Jackson, M., Gicquel, B., Kundu, M., and Basu, J.  (2010) An oligopeptide tansporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages. PLoS ONE  5 :  e12225 

Sureka K, Hossain T, Mukherjee P, Chatterjee P, Datta P, Kundu M, Basu J. (2010) Novel role of phosphorylation-dependent interaction between FtsZ and FipA in mycobacterial cell division.PLoS One. 5: e8590. 

Kundu, M., Pathak, S.K., Kumawat, K., Basu, S., Chatterjee, G., Pathak, S.,  Noguchi, T.,  Takeda, K.,  Ichijo, H., Thien,  C.B.F.,. Langdon, W.Y. and  and Basu, J. A tumor necrosis factor- and c-Cbl-dependent FLIP_S degradation pathway and its role in Mycobacterium tuberculosis-induced macrophage apoptosis   (2009) Nature Immunol. 10, 918-925 

Barik, S., Sureka, K., Basu, J., and Kundu, M. RseA, the SigE specific anti-sigma factor of Mycobacterium tuberculosis, is inactivated by phosphorylation-dependent ClpC1P2 proteolysis. (2010) Mol. Microbiol. doi.: 10.1111/j/1365-2958.2009.07008x 

Mukherjee, P., Sureka, K., Datta, P., Hossain, T., Barik, S., Das, K.P., Kundu, M., and Basu, J. Novel role of Wag31 in protection of mycobacteria under oxidative stress. (2009) Mol. Microbiol. 73, 113-119 

Basu, S., Pathak, S.K., Chatterjee, G., Pathak, S., Basu, J., Kundu, M. Helicobacter pylori protein HP0175 transactivates EGFR through TLR4 in gastric epithelial cells. (2008) J. Biol. Chem. 283, 32369-32376 

Sureka, K., Ghosh, B., Dasgupta, A., Basu, J., Kundu, M. and Bose, I. Positive feedback and noise activate the stringent response regulator Rel in mycobacteria. (2008) PLoS One, vol. 3, e1771. 

Pathak,  S.K., Basu, S., Basu,  K.K., Banerjee, A., Pathak,  S., Bhattacharyya, A., Kaisho, T., Kundu,  M., and Basu,  J. Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages. (2007) Nat Immunol. 8, 610-618  

Basu, S.,  Pathak, S.,  Pathak, S.K.,  Bhattacharyya, A.,  Banerjee, A.,  Kundu, M. and  Basu, J. Mycobacterium avium-induced matrix metalloproteinase-9 expression occurs in a cyclooxygenase-2-dependent manner and involves phosphorylation- and acetylation-dependent chromatin modification  (2007) Cellular Microbiology  9, 2804-2816

Basu, S.,  Pathak,  S.K., Banerjee, A., Pathak, S.,  Bhattacharyya, A.,  Yang, Z., Talarico, S., Kundu, M. and Basu, J. Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-α  (2007) J. Biol. Chem.  282, 1039–1050

Sureka, K., Dey, S., Datta, P., Singh, A.K., Dasgupta, A., Rodrigue, S., Basu, J., Kundu, M. Polyphosphate kinase is involved in stress-induced mprAB-sigE-rel signalling in mycobacteria. (2007) Mol. Microbiol. 65, 261-276 

Datta, P., Dasgupta, A., Singh, A.K., Mukherjee, P., Kundu, M., and Basu, J.  Interaction between FtsW and penicillin-binding protein (PBP)3 directs PBP3 to mid-cell, controls cell septation and mediates the formation of a trimeric complex involving  FtsZ, FtsW and PBP3 in mycobacteria (2006) Mol. Microbiol.  62, 1655–1673 

Pathak, S.K.,  Bhattacharyya, A., Basu, S., Banerjee, A., Basu, J., and Kundu, M.  TLR4-dependent NF-kB activation and mitogen- and stress-activated proteins kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidyl prolyl cis-, trans- isomerase (HP0175)-mediated induction of IL-6 release from macrophages. (2006) J. Immunol. 177, 7950-7958 

Mukherjee, P., Dutta, M., Datta, P., Dasgupta, A., Pradhan, R., Pradhan, M., Kundu, M., and Basu, J., and Chakrabarti, P. The RD1-encoded antigen Rv3872 of Mycobacterium tuberculosis as a potential candidate for serodiagnosis of tuberculosis. (2007) Clin. Microbiol.  Infect. 13, 146-152 

Kundu M, and Basu J.IL-32: An Emerging Player in the Immune Response Network against Tuberculosis? (2006) PLoS Med. 18, 3(8) 

Dasgupta, A., Datta, P., Kundu, M., and Basu, J. The serine/threonine kinase PknB of Mycobacterium tuberculosis phosphorylates PBPA, a penicillin-binding protein required for cell division. (2006) Microbiology, 152, 493-504   

Pathak,  S.K., Basu, S., Bhattacharyya, A., Pathak, S., Kundu, M. and  Basu J. Mycobacterium tuberculosis lipoarabinomannan-mediated irak-M induction negatively regulates Toll-like receptor-dependent interleukin-12 p40 production in macrophages. (2005) J. Biol. Chem. 280, 42794-42800 

Mandal, D., Mazumder, A., Das, P., Kundu, M. and Basu J.  FAS-, caspase 8-and caspase 3-dependent signaling regulate the activity of the aminophospholipid translocase and phosphatidylserine externalization in human erythrocytes. (2005) J. Biol. Chem. 280, 39460-39467 

Basak, C.,  Pathak, S.K.,  Bhattacharyya, A.,  Pathak, S.,  Basu, J.  and Kundu, M.  The secreted peptidyl prolyl cis,trans-isomerase HP0175 of Helicobacter pylori induces apoptosis of gastric epithelial cells in a Toll-like receptor 4 and apoptosis signal-regulating kinase 1(ASK1)-dependent manner. (2005) J. Immunol., 174, 5672-5680  

Toye, A.M, Ghosh, S., Young, M.T., Jones, G.K., Sessions, R.B., Ramaugé, M., Leclerc, P., Basu J., Delaunay, J. and Tanner ,M.J.A. Protein 4.2 enhances band 3 (AE1, SLCA4) induced anion transport in Xenopus oocytes: effects of three natural protein 4.2 mutations associated with hemolytic anemia. (2005) Blood 105, 4088-4095 

Pathak, S.K., Bhattacharyya, A., Pathak, S., Basak, C., Mandal, D., Kundu, M.and Basu, J. (2004) Toll-like receptor 2 and mitogen and stress-activated kinase 1 are effectors of Mycobacterium avium- induced cyclooxygenase-2 expression in macrophages. J. Biol. Chem.  279,  55127-55136 

Basu, J.  (2004)  Protein palmitoylation and dynamic modulation of protein function. Current Science 87, 212-216

Basu, J. (2004) Mycobacteria within its intracellular niche: survival of the pathogen or its host. Current Science 86, 103-110

Mandal, D., Baudin-Creuza, V., Bhattacharyya, A., Pathak, S., Delaunay, J., Kundu, M. and Basu, J. (2003) Caspase 3-mediated proteolysis of the N-terminal cytoplasmic domain of the human erythroid anion exchanger 1 (Band 3) (2003) J. Biol. Chem. 278,  52551-52558  

Bhattacharyya, A., Pathak, S., Basak, C., Law, S., Kundu, M. and Basu, J. (2003)Execution of macrophage apoptosis by Mycobacterium avium through apoptosis signal-regulating kinase 1/p38 mitogen-activated protein kinase signaling and caspase 8 activation. J. Biol. Chem. 278, 26517-26525.  

Datta, P., Dasgupta, A., Bhakta, S.,  and Basu, J. (2002) Interaction between FtsZ and FtsW of Mycobacterium tuberculosis. J. Biol. Chem. 277, 24983-24987.

Bhattacharyya, A., Pathak, S., Datta, S., Chattopadhyay, S,  Basu, J. and  Kundu, M. (2002) Mitogen-activated protein kinases and nuclear factor-kappaB regulate Helicobacter pylori-mediated interleukin 8 release from macrophages. Biochem. J. 368, 121-129.

Mandal, D., Moitra, P.K., Saha, S. and Basu, J. (2002) Caspase 3 regulates phosphatidylserine externalization and phagocytosis of oxidatively stressed erythrocytes. FEBS Lett. 513, 184-188. 

Bhattacharyya, A., Pathak, S., Kundu, M. and  Basu, J. (2002)Mitogen-activated protein kinases regulate Mycobacterium avium-induced  tumor necrosis  factor-a  release from macrophages. FEMS Immunol Med. Microbiol. 34, 73-80. 

Mandal, D., Moitra, P.K. and Basu, J. (2002)Mapping of a spectrin-binding domain of human erythrocyte membrane protein 4.2. Biochem. J. 364, 841-847. 

Bhakta, S. and Basu, J. (2002) Overexpression, purification and biochemical characterization of a class A high-molecular-mass penicillin-binding protein (PBP), PBP1* and its soluble derivative from Mycobacterium tuberculosis. Biochem. J.  361, 635-639. 

Choudhuri, B.S., Bhakta, S., Barik, R., Basu, J.,  Kundu, M. and Chakrabarti, P. (2002) Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB  of Mycobacterium tuberculosis. Biochem. J. 366, 279-285.

Maiti, D., Bhattacharyya, A., and Basu, J. (2001)Lipoarabinomannan from Mycobacterium tuberculosis promotes macrophage survival by phosphorylating Bad through a phosphatidylinositol 3-kinase/Akt pathway. J. Biol. Chem. 276, 329-333 

Mahapatra, S., Bhakta, S., Ahamed, J. and Basu, J. (2000) Characterization of derivatives of the high molecular mass penicillin-binding protein (PBP) 1 of Mycobacterium leprae  Biochem. J. 350, 75-80 

Bhattacharya, R.,  Das,  A. K., Moitra, P. K., Pal, B., Mandal, I.  and Basu, J. (1999) Mapping of a palmitoylable band 3-binding domain of human erythrocyte protein 4.2.  Biochem. J., 340, 505-512. 

Basu, D., Narayankumar, D.V., Van Beeumen, J. and Basu, J. (1997) Characterization of a beta-lactamase from Mycobacterium smegmatis SN₂. Biochem. Mol. Biol. International 43, 557-562. 

Kar, A.K., Ghosh, A.S., Ahamed, J., Chauhan, K., Basu, J., Chakrabarti, P. and Kundu, M. (1997) Involvement of a 43 kDa outer membrane protein in beta-lactam resistance of Shigella dysenteriae. Antimicrob. Agents Chemother., 41, 2302-2304. 

Lepage, S., Dubois, P., Ghosh, T., Joris, B., Mahapatra, S., Kundu, M., Basu, J., Chakrabarti, P., Cole,  S.T.,  Nguyen-Disteche, M. and Ghuysen, J.M. (1997)Dual multimodular class A penicillin-binding proteins in Mycobacterium leprae. J. Bacteriol., 179, 4627-4630. 

Das, A.K., Dasgupta, B., Bhattacharya, R. and Basu, J. (1997) Purification and biochemical characterization of a protein palmitoyl acyltransferase from human erythrocytes. J. Biol. Chem. 272: 11021-11025. 

Das,  A. K., Sinha,  A.K. and  Basu, J. (1997)Erythrophagocytosis and its relation to band 3 clustering in chronic myelogenous leukemia. Biochem. Mol. Biol. Int. 41: 539-545. 

Mukherjee, T., Basu, D., Mahapatra, S., Van Beeumen, J. and Basu, J. (1996) Biochemical characterization of the 49 kDa penicillin-binding protein of Mycobacterium smegmatis. Biochem. J. 320: 197-200. 

Srinivasan, P.T. and Basu, J. (1996) Altered membrane phospholipid organization and erythrophagocytosis in Eb-thalassemia. Biochim. Biophys. Acta 1285: 65-70. 

Basu, J., Mahapatra, S., Kundu, M., Mukhopadhyay, S., Nguyen-Disteche, M., Dubois, P., Joris, B., van Beeumen J., Cole, S.T., Chakrabarti, P. and Ghuysen, J.M. (1996) Identification and overexpression in Escherichia coli of a Mycobacterium leprae gene, pon1, encoding a  high-molecular-mass class A penicillin-binding protein PBP1. J. Bacteriol. 178: 1707-1711.  

Das, A.K., Bhattacharya, R., Kundu, M., Chakrabarti, P. and Basu, J. (1994) Human erythrocyte membrane protein 4.2 is palmitoylated. Eur. J. Biochem. 224, 575-580. 

Goswami, S., Sarkar  S., Basu,  J., Kundu,  M.  and Chakrabarti,  P.  (1994)  Mycotin: a lectin involved in the adherence of mycobacteria to macrophages. FEBS  Lett. 335: 183-186.

Mahapatra, S., Basu, J., van Beeumen, J. and Kundu, M. (1994)Characterization of a 38 kDa penicillin-binding protein and its possible involvement in maintaining stationary-phase cells of Shigella dysenteriae. Microbiology 140: 3177-3182. 

Basu, J., Chattopadhyay, R., Kundu, M. and Chakrabarti, P. (1992) Purification and partial characterization of a penicillin-binding protein from Mycobacterium smegmatis. J. Bacteriol. 174: 4829-4832. 

Basu, J., Kundu, M. and Chakrabarti, P. (1992)Purification of a phosphatidylinositol/phosphatidylcholine transfer protein from Neurospora crassa. Biochim. Biophys. Acta 1126: 286-290. 

Das, A.K., Kundu, M., Chakrabarti, P. and Basu, J. (1992)Fatty acylation of a 55 kDa membrane protein of human erythrocytes. Biochim. Biophys. Acta 1108: 128-132. 

Kundu, M., Basu, J. and Chakrabarti, P. (1991) Defective mycolic acid biosynthesis in a mutant of Mycobacterium smegmatis. J. Gen. Microbiol. 137: 2197-2200. 

Kundu, M., Basu, J., Fujimagari, M., Williamson, P., Schlegel, R.A. and Chakrabarti, P. (1991) Altered erythrocyte protein kinase C activity and membrane protein phosphorylation in chronic myelogenous leukemia. Biochim. Biophys. Acta 1096: 205-208. 

Kundu, M., Basu, J. and Chakrabarti, P. (1990) Chronic myelogenous leukemia: alterations in red cell membrane band 3 and increased IgG binding. Ind. J. Biochem. Biophys. 27: 456-459.

Kundu, M., Basu, J., Rakshit, M.M. and Chakrabarti, P. (1989)Abnormalities in erythrocyte membrane band 3 in chronic myelogenous leukemia. Biochim. Biophys. Acta 985: 97-100. 

Mazumder, C., Basu, J., Kundu, M. and Chakrabarti, P. (1990) Changes in membrane lipids and amino acid transport in a nystatin-resistant mutant of Aspergillus niger. Can. J. Microbiol. 36: 435-437. 

Kundu, M., Basu, J., Rakshit, M.M. and Chakrabarti, P. (1989) Abnormalities in the erythrocyte membrane in acute lymphoid leukemia. Biochem. J. 258: 903-906. 

Kundu, M., Basu, J. and Chakrabarti, P. (1989) Lectin from Mycobacterium smegmatis. FEBS Lett. 256: 207-210. 

Mazumder, C., Kundu, M., Basu, J. and Chakrabarti, P. (1989)Liposome-trapped nystatin in growth inhibition of Aspergillus niger. J. Liposome Res. 1: 167-175. 

Basu, J., Kundu, M., Rakshit, M.M. and Chakrabarti, P. (1988) Abnormal erythrocyte membrane cytoskeleton structure in chronic myelogenous leukemia. Biochim. Biophys. Acta 945: 121-126. 

Kundu, M., Basu, J. and Chakrabarti, P. (1988) Studies on a lectin from Saccharomyces cerevisiae. Ind. J. Biochem. Biophys. 25: 204-208. 

Basu, J., Kundu, M., Bhattacharya, U., Mazumder, C. and Chakrabarti, P. (1988) Purification and characterization of a non-specific lipid transfer protein from goat liver. Biochim. Biophys. Acta 945: 134-142. 

Mazumder,  C., Kundu,  M., Basu,  J.  and  Chakrabarti, P. (1987) Lipid composition and amino acid transport in a nystatin-resistant mutant of Aspergillus niger.  Lipids 22: 609-612. 

Kundu, M., Basu, J., Ghosh, A. and Chakrabarti, P. (1987)Chemical modification studies on a lectin from Saccharomyces cerevisiae.(baker’s yeast). Biochem. J. 244: 579-584. 

Kundu, M., Basu, J., Guchhait, M. and Chakrabarti, P. (1987) Isolation and characterization of an extracellular lipase from Neurospora crassa. J. Gen. Microbiol. 133: 149-153. 

Basu, J., Kundu, M. and Chakrabarti, P. (1986) Effect of fatty acid supplementation on the thermotropic behavior of membrane lipids and leucine transport in Saccharomyces cerevisiae. Arch. Biochem. Biophys. 250: 352-359. 

Basu, J., Kundu, M., Mukherjee, K. and Chakrabarti, P. (1986) Release of a lectin from a fatty acid auxotroph of Saccharomyces cerevisiae grown in the presence of oleic acid. Biochem. Biophys. Res. Commun.136: 596-602.