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Nripendranath Mandal, Ph.D.
Associate Professor
Division of Molecular Medicine
(Formerly Immunotechnology
Section)
Ph.D.(Biochemistry): IICB,
University of Calcutta (1990)
Tel: 91-33-2569-3285
Fax: 91-33-2355-3886
E-mail:nripen@bic.boseinst.ernet.in
drnmandal@gmail.com
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Themes of research:
The central theme of research program in my
laboratory has been initiated in the field of Marine Biotechnology and
Medical Biotechnology for disease management in aquatic organism and
human system, for welfare of the people with the help of modern science and
technology. Our primary focus is to address the basic socio-economic
problems of some important diseases and to find out inexpensive way of their
solution in aquatic organism as well as human system.
Current Research Interest:
● Development of various DNA/RNA markers in
giant black tiger shrimp (Penaeus monodon) to identify the White spot
syndrome virus (WSSV) resistant population of Penaeus monodon, and at
the same time understand the molecular pathogenesis of white spot disease in
shrimp.
● Development of scientific evidences for Indian
system of traditional medicine, by isolation and characterization of active
principles from medicinal herbs, along with multi-dimensional determination
of their bio-activities for the potentials of antioxidant, anticancer,
anti-inflammatory, anti-diabetic etc.
Current group members Previous group
members
1.
Mr. Bibhabasu Hazra
1. Dr. Santanu Biswas
2.
Mr. Rhitajit Sarkar
2. Dr. Kuntal Mukherjee
3.
Mr. Sourav Dutta
3. Dr. Arnab Ghosh
4.
Ms. Usri Chakrabarty
4. Dr. Srikanta Jana
5.
Mr. Ajoy Mallik
5. Dr. Eliza Chakrabarty
6.
Mr. Nikhil Baban Ghate
6. Dr. Selvamani Vijaylingam
7.
Mr. Dipankar Chaudhuri
8.
Mr. Ranjit Kumar Das
9.
Mr. Pradip Kumar Mallick
Publications
during last five years
1.
Dutta S., Chakrabarty U., Mallik A. and
Mandal N.
(2012)
Experimental evidence for WSSV susceptibility linked to a microsatellite DNA
marker in Giant Black Tiger Shrimp,
Penaeus monodon
(Fabricius).
Journal of Fish Diseases
(In press)
2.
Hazra, B., Sarkar, R. and
Mandal, N.
(2012)
Protection of
Terminalia
Belerica
Roxb. Against Iron Overload Induced Liver Toxicity: An Account of Its
Reducing and Iron Chelating Capacity
American Journal of Pharmacology and Toxicology
7 (3), 109-122,
DOI: 10.3844/ajptsp.2012.109.122
3.
Sarkar, R., Hazra, B. and
Mandal, N.
(2012)
Reducing
power and iron chelating property of
Terminalia chebula
(Retz.) alleviates iron induced liver toxicity in mice
BMC
Complementary and Alternative Medicine
12:144 doi:10.1186/1472-6882-12-144
4.
Sarkar, R., Hazra, B. and
Mandal, N.
(2012)
Hepatoprotective potential of
Caesalpinia crista
against iron overload induced liver toxicity in mice
Evidence-based Complementary and Alternative Medicine
Volume 2012, Article ID 896341, 9 pages doi:10.1155/2012/896341
5.
Roy, S., Hazra, B.,
Mandal,
N.
and Chaudhuri, T.K. (2012)
Assessment of the Antioxidant and Free Radical Scavenging Activities of
Methanolic Extract of
Diplazium
esculentum
International Journal of Food Properties
(ID:587382 DOI: 10.1080/10942912.2011.587382)
6.
Hazra, B., Sarkar, R., Biswas, S. and
Mandal, N.
(2011)
Antioxidant and iron chelating potential of
Pongammia pinnata
and its role in preventing free radical induced oxidative damage in plasmid
DNA
International Journal of phytomedicine
3, 240-253
7.
Hazra, B., Sarkar, R., Biswas, S. and
Mandal, N.
(2010)
Comparative study of the antioxidant and reactive oxygen species scavenging
properties in the extracts of the fruits of
Terminalia chebula,
Terminalia belerica and Emblica officinalis
BMC
Complementary and Alternative Medicine
10:20 doi:10.1186/1472-6882-10-20
8.
Biswas, S., Ghosal, P.K., Mandal, S.C. and
Mandal, N.
(2010)
Relation of
anti- to pro-inflammatory cytokine ratios with acute myocardial infarction.
The
Korean Journal of Internal Medicine
25(1): 44–50. Published online 2010 February 26. doi:
10.3904/kjim.2010.25.1.44.
9.
Hazra, B., Sarkar, R., Biswas, S. and
Mandal, N.
(2010)
The
Antioxidant, Iron Chelating and DNA Protective Property of 70% Methanolic
Extract of “Katha” (Heartwood extract of
Acacia catechu)
Journal of Complementary and Integrative Medicine
Volume 7 : Issue 1, Article 5, doi: 10.2202/1553-3840.1335.
10.
Sarkar, R., Hazra, B., Mandal, S., Biswas, S. and
Mandal, N.
(2009)
Assessment
of in vitro antioxidant and free radical scavenging activity of
Cajanus cajan.
Journal of Complementary and Integrative Medicine
Volume 6, Issue 1 Article 24, doi: 10.2202/1553-3840.1248.
11.
Mandal, S., Hazra, B., Sarkar, R., Biswas, S. and
Mandal, N.
(2009)
Assessment
of the antioxidant and reactive oxygen species (ROS) scavenging activity of
methanolic extract of Caesalpinia crista
leaf.
Evidence-based Complementary and Alternative Medicine
doi:10.1093/ecam/nep072.
12.
Mandal, S., Hazra, B., Sarkar, R., Biswas, S. and
Mandal, N.
(2009) Hemidesmus indicus,
an age old plant: study of its in vitro antioxidant and free radical
scavenging potentials.
Pharmacologyonline
1:604-617.
13.
Mukherjee, K. and
Mandal, N.
(2009)
A
microsatellite DNA Marker developed for identifying disease resistant
population of Giant Black Tiger Shrimp (Penaeus monodon).
Journal of World Aquaculture Society
40:274-280.
14. Hazra,
B., Biswas, S. and
Mandal, N.
(2008)
Antioxidant
and free radical scavenging activity of
Spondias pinnata.
BMC
Complementary and Alternative Medicine
8:63 doi:10.1186/1472-6882-8-63
15.
Biswas, S., Ghosal, P.K., Mandal, S.C. and
Mandal, N.
(2008)
Association
of low-density lipoprotein particle size and ratio of different lipoproteins
and apolipoproteins with coronary heart disease.
Journal of Cardiology
52:118-126
Patents
1.
Mandal, N.
and Mukherjee, K. A Microsatellite DNA marker used for identifying disease
resistant populations of Penaeus monodon
(filed in India on November 21, 2005 Application No. 1054/kol/2005 Publication
date: July 27, 2007).
2.
Mandal, N.
and Mukherjee, K. A Microsatellite DNA marker used for identifying disease
resistant populations of Penaeus monodon
[International Patent filed on March 22, 2006 (Vietnam,
Thailand, Malaysia, Singapore, Philippines and Indonesia)
Application No. PCT/IN06/00101, Publication No. WO/2007/057915 and
Publication date on May 24, 2007].
[Details of Publications]
Awards
1.
Bharat Jyoti Award
2.
Glory of India Gold Medal
3.
Rajiv Gandhi Excellence Award
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