Microtubule is a nanowire or polymer of proteins found in the living eukaryotic cells. They came into this earth long back, that very single nanowire has evolved into millions of different species in billions of years. Enormous amount of distinct functionalities were born from this single nanowire. This is truly unbelievable, whenever, a species require to evolve, microtubule makes small changes in the same very protein that is existing for ages and delivers the necessary functionalities to the species. If Antarctic fish requires making microtubule at very low temperatures, microtubule does that amicably, then prepares flagela for swimming, even a major component of neuron in our brain. How is that possible? Do we know about any technology made by mankind depicting this behavior? This is not the end, just the beginning of a remarkble journey to explore this nanowire. To remember information, it does not cost any energy. Even if we try to increase its conductivity by raising temperature, it does not respond, the path remains non-responsive. How microtubule is able to create an architecture where heat does not have any effect? While we mankind are trying to ignore heat using radiators, microtubule has learnt to survive with heat collectively. Technological approach of microtubule is all the way different. We always talk about one resonance frequency, microtubule talks as octave quantum oscillator. It is a beautiful quantum drum inside our brain that sings in the sub-sonic and ultrasonic domain.