| |
 Pinakpani
Chakrabarti
Professor, Biochemistry
PhD: Indian Institute of Science, Bangalore, 1981
Research interest
Understanding the structure and folding of proteins and
their interactions with other molecules, large and small, using biophysical
techniques (especially, X-ray crystallography) and database analysis. Some
specific topics are:
-
Identification of
stabilizing interactions (like CH-p,
CH-O,
electrophile-nucleophile,
aromatic-aromatic
etc.) and their geometry
-
Analysis of protein
conformation
-
Protein folding, threading
and prediction of structures
-
Molecular modelling and
dynamics
-
Molecular recognition,
protein-protein complexation and ion-binding by proteins
-
Crystallography of proteins
from phage lambda
-
Molecular design and
docking
-
Bioinformatics and
proteomics
-
Crystal packing and
supramolecular assembly
Name of group members
|
Name |
Period of stay |
Working for/as |
Presently at |
|
Shrihari Sonavane |
Sept, 2004 – present |
PhD |
|
|
Arumay Pal |
Sept, 2003 – present |
PhD |
|
|
Mainak Guharoy |
Sept, 2003 – present |
PhD |
|
|
Sumit Biswas |
Aug, 2002 – present |
PhD |
|
|
Bhaskar Dasgupta |
Oct, 2001 – present |
PhD |
|
|
Rudra Prasad Saha |
July, 2001 – present |
PhD |
|
|
Rajasri Bhattacharyya
|
Dec, 1999 – present |
PhD/RA |
|
|
Ranjit Prasad Bahadur
|
Aug, 2000 – August, 2005 |
PhD |
Université Paris-Sud |
|
Saptarshi Mandal |
Sept, 2003 – June, 2004 |
PA |
Anshin Software Pvt. Ltd.,
Kolkata |
|
Tarun K. Mandal |
Aug, 2003 – July, 2004 |
PA |
Haldia Inst Tech |
|
Ajit B. Datta |
Aug, 1997 – Nov, 2004 |
PhD |
Cornell Univ |
|
Lipika Pal-Ray |
Aug, 2002 – April, 2005 |
RA |
Univ Albany |
|
Debnath Pal |
Aug, 1995 – Oct, 2000 |
PhD |
Indian Institute Science |
|
Uttamkumar Samanta |
July, 1994 – Mar, 2001 |
PhD/RA |
Univ Delaware |
Important publications (ten)
- Guharoy M and Chakrabarti P (2005).
Conservation and relative importance of residues across protein-protein
interfaces. Proc. Natl. Acad. Sci. USA, 102, in press.
- Datta AB, Panjikar S, Weiss MS, Chakrabarti
P and Parrack P (2005). Structure of CII:
implications for recognition of direct-repeat DNA by an unusual
tetrameric organization. Proc. Natl. Acad. Sci. USA, 102, 11242-11247.
- Bahadur RP, Chakrabarti P, Rodier F and
Janin J (2004). A dissection of specific and non-specific
protein-protein interfaces. J. Mol. Biol. 336, 943-955.
- Bhattacharyya R and Chakrabarti P (2003).
Stereospecific interactions of proline residues in protein structures
and complexes. J. Mol. Biol. 331, 925-940.
- Pal L, Chakrabarti P and Basu G (2003).
Sequence and structure patterns in proteins from an analysis of the
shortest helices: implications for helix nucleation. J. Mol. Biol. 326,
273-291.
-
Chakrabarti P and Pal D (2001). The interrelationships of side-chain and
main-chain conformations in proteins. Prog. Biophys. Mol. Biol. 76,
1-102.
- Pal D and Chakrabarti P (1999). Cis peptide
bonds in proteins: residues involved, their conformations, interactions
and locations. J. Mol. Biol. 294, 271-288.
- Chakrabarti P and Chakrabarti S (1998).
CHO hydrogen bond involving proline residues in -helices. J. Mol.
Biol. 284, 867-873.
- Chakrabarti P and Samanta U (1995). CH/
interaction in the packing of the adenine ring in protein structures. J.
Mol. Biol. 251, 9-14.
- Chakrabarti P (1993). Anion binding sites
in protein structures. J. Mol. Biol. 234, 463-482.
To see the list of full publications,
click
here.
Contact
pinak@boseinst.ernet.in,
pinak_chak@yahoo.co.in |
