 Swati
Sen-Mandi
Senior Professor and Consultant Scientist
ICMR Emeritus Medical Scientist (From September-2012)
Awards and Honours:
·
Gold Medal
and Silver Medal of Calcutta University for Class I, 1st
rank in M.Sc. (Botany 1970)
·
State Scholarship
(Government of West Bengal) for undertaking Ph.D programme in
Agricultural Research Council Unit of Developmental Botany, Cambridge
University, U. K., 1972-1975.
·
Gulbenkian Studentship,
Churchill College, Cambridge, U.K, supplementing State Scholarship
amount for carrying out Ph.D programme at Cambridge University, UK.,
1972- 1975
·
Fulbright Senior Visiting Fellow
at Department of Vegetable Crops, University of California, Davis,
USA, Oct. 1985-March 1986
·
Visiting Scientist (Research Fellow 3)
at International Network for Genetic Evaluation of Rice (INGER) in
International Rice Research Institute (IRRI), Philippines, May,
1990 – April, 1991
·
National Science Foundation (NSF), USA,
Visiting Scientist at the Department of Agronomy, Ohio State
University, USA 1991.
·
Visiting Scientist on a research collaboration programme at Rothamsted
Experimental Station, Harpenden, U.K. March 1994, Sponsored by
British Council.
·
Nominated Representative for India
in the International Society of Seed science,
1999.
·
Rockefeller Foundation Residency
at Bellagio Study and Conference Centre, Italy, to work on a
manuscript entitled “Seed Quality and Seedling vigour for sustainable
Agriculture: New prospects by molecular screening”, Feb-March, 2001
·
DAAD Fellowship for Study and Research
at Institute of Crop Science and Plant Breeding, Christian-Albrechts-University,
Kiel, Germany, Oct – Dec. 2001.
·
Invited Associate Editor
of the International Journal of Seed Technology,
2010.
Research interest
·
Develop comprehensive
understanding, involving plant physiological, biochemical and molecular
biological concepts, towards plant survival and perpetuation under natural
UV irradiation on earth .The study focuses on an important agronomic
crop(viz. rice) and an important cash crop(viz. tea). The aspects of study
include:
a) Demonstration of the role of UV irradiation in conferring plant survival
and quality with special reference to high levels of antioxidant and aroma
in Darjeeling tea leaf. This invention would help to enhance aroma in tea
leaf at non-conventional cultivation sites.
b) Establishing a DNA marker associated with important agronomic traits viz.
vigour and viability of orthodox seed (viz. rice) during seed maturation on
field grown plants and post harvest seed storage in farmers’ storage.
This DNA marker is not only useful in wild germplasms screening but also is
useful for breeders in incorporating high vigour-viability traits into
otherwise elite varieties. This DNA marker would be useful for Quality
control of seeds to be sold by commercial seed companies to
cultivators/growers.
·
Documentation and
Evaluation of medicinal plant genetic resource, particularly of the hot spot
region viz. NE India through:
a) development of Species Specific DNA Markers that in addition to
providing precise Documentation data, also serves to supplement conventional
drug assessment protocol for production of herbal medicine.
b) development of Trait Related DNA Markers for identification of
non-conventional plant source of important medicinal compounds through wild
germplasm screening .
Current Research Activity:
Focuses mainly on
a)
Documentation of
medicinal plant genetic resource through DNA fingerprinting analysis using
appropriate methods viz. RAPD, ISSR, AFLP, SNP.
b)
Evaluation of medicinal
potential through modern chemical analysis of bioactive compounds in same
plant at different location/season.
c)
Studying
season/environment/location based variation in bioactive compounds of
medicinal importance with an aim to distinguishing between their genetic and
epigenetic controls.
d)
Human Resource
Development among young researchers particularly of Universities and
Research Institutes of Eastern and North Eastern India in the context of
Hands-on-Training for Molecular Documentation of important medicinal plants
with an aim towards transfer of such technology to appropriate laboratories
in the North East.
Name of Group members with present status:
a)
Dr. Sangita Dey (Research Associate, ICMR Project)
b)
Dr. Harshata Pal (Research Associate, ICMR Project)
c)
Mr. Subhabrata Ghosh (ICMR adhoc Senior Research Fellow)
d)
Mr. Shekhar Ghosh (Project Fellow, ICMR Project)
e)
Mr. Debmalya Dasgupta (Project Fellow, ICMR Project)
f)
Mr. Susanta Chatterjee (Technical Assistant, ICMR Project)
g)
Mr. Arup Nayak (Technical Assistant, ICMR Project)
h)
Mr. Sidhhartha Roy (Helper-C)
Recent Ph.D:
Subhra Talai (2012) Calcutta University (Thesis Title-Development of
Bio-Molecular Markers for Vigour in Rice seeds)
Sudeshna Bhattacharya (2012) Jadavpur University (Thesis Title-Cell
Molecular studies on Spontaneous Radiation Namely UV Stress Tolerance in
Plants)
Research Publications:
Sen,S.
and Osborne, D.J., 1974, Germination of rye embryos following hydration
dehydration treatments: Enhancement of protein and RNA synthesis and
earlier induction of DNA replication, J. Expt. Bot.,
25: 1010-19.
Sen, S.,
Payne, P.I. and Osborne, D.J., 1975, Early ribonucleic acid synthesis
during the germination of Rye (Secale cereale) embryos and the
relationship to early protein synthesis, Biochem. J.,
148:-381-87.
Sen, S
and Osborne, D.J., 1977, Decline in ribonucleic acid and protein
synthesis with loss of viability during the early hours of imbibition of
Rye (S. cereale L) embryos, Biochem. J.,
166:
33-38.
Sargent,
J.A.,
Sen, S.
and Osborne, D.J., 1981, The loss of desiccation tolerance during
germination : An ultrastructural and biochemical approach,
Protoplasma,
105:
225-239.
Bhattacharyya (Ganguli) S. and
Sen-Mandi, S.,
1985, Studies into causes of non-germination of aged wheat seed, Ann.
Bot.,
56:
475-479.
Bhattacharyya (Ganguli) S., Hazra, A.K. and
Sen-Mandi, S.,
1985,
Accelerated ageing of seeds in hot water : Germination characteristics
of the aged what seed, Seed Sci. Technol.,
13(3): 683-690.
Das, G.
and
Sen-Mandi, S.,
1988,
Root formation in deteriorated (aged) wheat embryos, Plant Physiol.,
88(4):
983-987.
Ganguli,
S., Das, G. and
Sen-Mandi, S.,
1990, Some physiological differences between naturally and artificially
aged wheat seeds, Seed Sci. Technol.,18:507-514.
Das, G.
and
Sen-Mandi, S.,
1992,
Utilization of free fatty acids during early germination of unaged and
differentially aged wheat embryos, Ind. J of Exp. Biol.,
30: 299-301
Ganguli,
S. and
Sen-Mandi, S.,
1992,
DNA protecting role of chromatin histones in aged wheat embryos, Ind.
J of Exp. Biol. ,
30:
636-639.
Das, G.
and
Sen-Mandi, S.,
1992,
Triphenyl tetrazolium chloride staining pattern of differentially aged
wheat seed /embryos, Seed Sci. Technol.
, 20: 367-373.
Ganguli,
S. Das G. and
Sen-Mandi, S.,
1992, Plant emergence and productivity of different vigour of wheat (Triticum
aestivum) seeds, Ind. J of Agric. Sci., 62(3): 224-227.
Rajagopal, (Dass) ASM and
Sen-Mandi, S.,
1992,
Studies on acid and alkaline phosphatases in aged rice embryos, Seed
Sci. Technol.,
20:215-222.
Das, G.
and
Sen-Mandi, S.,1992,
Scutellar amylase activity in naturally aged and accelerated aged wheat
seeds, Ann. Bot.,
69: 497-501.
Ganguli,
S. and
Sen-Mandi, S.,
1993,
Effects of ageing on amylase activity and scutellar cell structure
during imbibition in wheat seed, Ann. Bot.,
71:
411-416.
Ganguli,
S. and
Sen-Mandi, S.,
1995,
Embryo rescue from non-viable seeds for preservation of wheat (Triticum
aestivum) germplasm,
Ind. J.
Agric. Sci.,
65(11): 781-784.
Nandi,
S., Ganguli, S.and
Sen-Mandi, S.,
1995.
Seed technology for cold tolerance in rice, IRRN , 20(1):20-21.
Nandi,
S., Das, G. and
Sen-Mandi, S.,
1995,
b-amylase
activity as an index for germination potential in rice, Ann. Bot.,
75: 463-467.
Nandi,
S., Das, G. and
Sen-Mandi, S.,
1996, Biochemical response to cold acclimatization in rice seeds,
Pl. Physiol. Biochem., 23(2): 199-204.
Nandi,
S.,
Sen-Mandi., S.
and Sinha T. P., 1997, Active oxygen and their scavengers in rice seeds
(Oryza sativa cv. IET4094) aged under tropical environmental conditions,
Seed Sci. Res.,
7:
253-259.
Nandi,
S., Subudhi, P. K., Senadhira, D., Manigbas, N. L.,
Sen-Mandi, S.
and Huang, N.,
1997, Mapping QTLs for submergence tolerance in rice by AFLP analysis
and selective genotyping, Mol. Gen. Genet., 255: 1-8.
Das, G.,
Raj, S., Pothen, J.,Sethuraj, M.R., Sinha, T.P. and
Sen-Mandi, S.,
1998, Status of free
radical and its scavenging system with stimulation in Hevea
brasiliensis., Pl. Physiol.Biochem., 25(1):
47-50
Mishra,
R.K.
and Sen-Mandi, S.,
2001,
DNA fingerprinting and Genetic relationship study of tea plants using
Amplified Fragment Length Polymorphism (AFLP) technique, Indian J of
Plant Genetic Resources, 14(2):
148 –
149.
Das, G.,
Alam, B., Raj, S., Dey S.K., Sethuraj, M.R and
Sen-Mandi, S.,
2002,
Over-exploitation Associated Changes in Free Radicals and its Scavengers
in Hevea brasiliensis, J.Rubb.Res.,
5(1):
28-40.
Sen-Mandi, S and
Bhattacharya, S.,
2003,
Varietal difference in cellular damage associated with ageing in dry
stored seed, Special issue of Ind. J. Pl Physiol.,
210-216.
Mishra,
R.K. and
Sen-Mandi, S.,
2004,
Molecular Profiling and Development of DNA marker associated with
Drought Tolerance in Tea Clones growing in Darjeeling, Curr Sc.,
87(1):
60-66.
Talai, S and Sen-Mandi, S., 2010, Seed vigour-related DNA
marker in rice shows homology with Acetyl CoA Carboxylase gene, Acta
Physiol. Plant., 32:153-167.
Sanatombi K. Sen-Mandi, S. and Sharma G.J., 2010, DNA profiling
of Capsicum landraces of Manipur, Scientia Horticulturae,
124: 405–408.
Ghosh, S., P.B.Majumdar, S. Sen-Mandi 2011. Species Specific AFLP
markers for identification of Zingiber officinale, Z. montanum
and Z. zerumbet (Zingiberaceae). Genetics and Molecular
Research, 10(1):218-229.
Bhattacharya Sudeshna and Swati Sen-Mandi 2011. Variation in
antioxidant and aroma compounds at different altitude: A study on tea (Camellia
sinensis L.Kuntze) clones of Darjeeling and Assam, India. African
Journal of Biochemistry Research 5(5): 148-159.
Subhabrata Ghosh, Sayanika Waikhom Devi, Swati Sen Mandi, Narayan
C Talukder 2011. Amplified Fragment Length Polymorphism based study of
phylogenetic relationship and genetic variability among some edible
Bamboo species of North-East India J. Plant Mol. Biol. Biotechnol 2:
(2) 8-15.
Raina,
S.N., P.S. Ahuja, R. K. Sharma, S. C.Das, P. Bhardwaj, R. Negi, V.
Sharma, S.S.Singh, R. K. Sud, R. K.Kalia, V. Pandey, J. Banik, V. Razdan,
D. Sehgal, T.H.Dar, A. Kumar, S. bali, V. Bhat, S. Sharma, B.M.Prasanna,
S. Goel, M.S.Negi, P. Vijayan, S.B.Tripathi, B. Bera, M. Hazarika,
A.K.A. Mandal, R.R.Kumar, D. Vijayan, S. Ramkumar, B.R. Chowdhury and
S.S. Mandi.,
2011,
Genetic structure and diversity of India hybrid tea. Genet. Resour.
Crop. Evol. DOI 10.1007/s 10722-011-9782-6.
Choudhury, S.S. and
S.S.Mandi
2012. Natural Ultra Violet Irradiance related variation in antioxidant
and aroma compounds in tea (Camellia sinensis L. Kuntze) plants
grown in two different altitudes. International Journal of
Environmental Biology 2 (1):1-6.
Shyam
Choudhury, S. and Sen Mandi, S. (2012): Natural ultraviolet
radiation on field
grown rice (Oryza
sativa L.) plants confer protection against oxidative stress in seed
during storage under subtropical ambience. Environment and Pollution,
1(2): 21-32.
Contribution of chapters
in books, conference volumes:
Osborne, D.J., Robert, B.E., Payne, P.I. and Sen, S. 1974.
Protein synthesis and viability in rye embryos. In Mechanisms of
Regulation of Plant Growth (Bieleski, R.I. and Ferguson, A.R., Eds)
Bulletin 12: 805-812.
Osborne, D.J., Dobzranska, M. and Sen, S. 1977. Factors
determining nucleic acid and protein synthesis in the early hours of
germination. In Integration of Activity in the Higher Plant. Symposia
of the Society for Experimental Biology: 177-94.
Sen-Mandi, S., Nandi, S., Das, G. and
Chakraborti, S. 1995. Bio-molecular and physiological studies on
hydration-dehydration seed invigoration pretreatment: An attempt to
overcome constraints of wet seeding in rice. International workshop on
"Constraints, opportunities and innovations of wet-seeded rice". IRRI.
Discussion Paper, Series (Edited by K. Moody) No. 10: 199-218.
Sen-Mandi, S., 1997.
Genetic Evaluation of Flora in High Altitude: Necessity of
the DNA Typing and Storage of Germplasm in “Science at High Altitude”,
Procedings of the National Symposium, Darjeeling,
Editors- Raha.
S., Ray P. K. and Sinha. B. 154-163.
Swati Sen-Mandi 2003.
Conservation Measures for Biodiversity with Special Reference to
Important Crops of West Bengal—Response Biodiversity conservation.
Proceedings of the Round Table
discussion.
(Under
EMCBTAP & ENVIS Programme). Department of Environment, Govt. of W. B.
Kolkata
Sen-Mandi S., Bhattacharya, S and
Talai, S. 2004. Functional Genomics of rice seed storability; a
gene mediated positive effect of spontaneous UV radiation.
Proceedings of Plant Genomics European Meetings, Lyon. P.073
Swati Sen-Mandi 2004.
Genotyping for documentation of Useful Genetic Resource with Special
Reference to Plants.
Lecture Notes. Workshop on Biodiversity for Generating Wealth with
Biotechnological Intervention.
Organized and sponsored by Institute of Life Sciences, Bhubaneswar.
Co-sponsored by: State Biotechnology Board, Orissa.
Patents
Awarded:
·
Indian Patent no. 216326 was awarded to Prof. Sen-Mandi in 2008 for
development of rice seed vigour related DNA marker.
·
Indian Patent no. 266488 was awarded to Prof. Sen-Mandi in 2008 for
developing drought tolerance related DNA marker in tea plants.
·
International Patent no. KE 392 was awarded to Prof. Sen-Mandi in 2010
for demonstration of effect of UV on antioxidants and aroma in tea leaf.
Contact
Prof. Swati Sen Mandi
Division of Plant Biology
Bose Institute (Main Campus)
93/1 A.P.C Road
Kolkata-700009
Phone: (033)23031125(O)
919830688067(M)
Email:
senmandi.swati@gmail.com
swatism@bosemain.boseinst.ernet.in
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