Dr. Subrata Majumder, Ph.D.

List of Publications

 Publication at Bose Institute :

  1. Ghosh, S., Pal, S., Das., S, Dasgupta, S. and Majumdar, S. (1998). Lipoarabinimannan induced altered signaling mechanism in human    peripheral blood mononuclear cells. FEMS Med Microbiol. Immunol. 21:   181.

  2. Das. S., Bhattacharyya, S., Ghosh, S.,. and Majumdar, S. (1999). TNF-a induced altered signaling mechanism in human neutrophil. Mol. Cell. Biochem. 197: 97.

  3. Mukhopadhyay, S., Sen, P., Bhattacharyya, S., Majumdar, S. and Roy, S. (1999). Immunoprophylaxis and immunotherapy against experimental Visceral Leishmaniasis.  VACCINE, 17: 291.

  4. Roy, K.,  Mandal, A. K., Sikdar, S., Majumdar, S., Ono, Y and Sen P. C.    (1999). Unsaturated  fatty acid-activated protein kinase (PKx) from goat testis   cytosol. Biochim. Biophys. Acta  1434: 161.

  5. S. Das, S. Bhattacharyya, S. Ghosh, S. Majumdar.(2000). Signal transduction mechanisms in neutrophil: comparative study between  and -protein kinase isotypes. Molecular and Cellular Biochemistry. 203: 143-151.

  6. S. Mukhopadhaya, S. Bhattacharyya, R. Majhi, T. De, K. Naskar, S. Majumdar, S. Roy. (2000). Use of attenuated leishmanial parasite as an immunoprophylactic an immunotherapeutic agent against murine visceral leishmaniasis. Clinical and Diagnostic Laboratory Immunology. 7: (2). 330

  7. Gupta, S.K., Majumdar, S., Mondal, A., and Dutta, A. (2000). Topical cyclophosphamide in the treatment of bone and joint infection. Ind. J. Orthopaed. 34 (4): 224

  8. Bhattacharya, S., Ghosh, S., Jhonson, P.L.., Bhattacharya, S.K. and Majumdar. S. (2001) Immunomodulatory role of IL-10 in visceral leishmaniasis: Defective activation of PKC mediated signal transduction events. Infection and Immunity. 69(3): 1499-1507

  9. Bhattacharya, S., Ghosh, S., Sen,P., Roy, S. and  Majumdar. S. (2001)  Selective impairment of protein kinase C isotypes in murine macrophages by Leishmania donovani. Molecular and cellular Biochem.  216: 47-57.

  10. Ghosh, S., Bhattacharyya, S., Das, S., Raha, S., Maulik, N., Das, D.K.,   Roy, S and Majumdar, S. (2001).  Generation of ceramide in murine macrophages infected with Leishmanial donovani alters macrophage signaling events and aids intracellular parasitic survival. Molecular and cellular Biochem.  223: 47-60.

  11. Bhattacharyya S., Ghosh S, Dasgupta B, Majumdar D, Roy S and Majumdar S (2002).  Chemokine induced Leishmanicidal activity in murine macrophages via generation of Nitric oxide. The journal of Infectious diseases 185:  1704-8.

  12. Ghosh S, Bhattacharyya S, Sirkar M, Sa GS, Das T, Majumdar D, Roy S and Majumdar S.(2002). Leishmanial donovani suppresses activated protein 1 and NF-kB  activation in host macrophages via ceramide generation: Involement of extracellular signal regulated kinase. Infection and Immunity . 70(12): 6828-6838.

  13. Sirkar M and Majumdar S. (2002). Lipoarabinomannan induced cell signaling involves ceramide and mitogen activated protein kinase. Clinical and Diagnostic laboratory Immunology. 9(6): 1175-1182.

  14. Dey, R., Sarkar, A., Majumder, N., Majumdar-Bhattacharyya, S., Roychoudhury, K., Bhattacharyya, S., Roy, S. and Majumdar, S. (2005). Regulation of impaired protein kinase C signaling by Chemokines in murine macrophages during  visceral leishmaniasis. Infection and Immunity. 73(12): 8334-8344.

  15. Das D., Saha A., Das S., Majumder N., Pal Chaudhury S., Majumder S. and Dey S., (2005)  Danger of heavy metal toxicity: Effect of lead on male reproductive system. Published in book Combating Disaster: Perspectives in the new Millennium. Acb publications India. 27-32.

  16. Majumder, N., Dey, R., Mathur, R.K., Datta, S., Maitra, M., Ghosh, S., Saha. B., and Majumdar, S (2006). An  unusual  proinflammatory role of interleukin-10 induced by arabinosylated lipoarabinomannan in murine peritoneal macrophages. Glycoconjugate J.  Vol. 23 (9).  675-686.

  17. Sharma, A., Saha, A., Bhattacharjee, S., Majumdar, S. and Das Gupta, S. K. (2006).  Specific and randomly derived immunoactive peptide mimotopes of mycobacterial antigens.  Clin. And Vaccine Immunology. Vol. 13 (10): 1143-1154

  18. Dey, R., Majumder, N., Bhattacharjee, S., Majumdar-Bhattacharyya, S. Banerjee. R., Ganguly. S., Das, P. and Majumdar, S. (2007). Leishmania donovani  induced ceramide as the key mediator of Akt dephosphorylation in murine macrophages: Role of PKC-and phosphatase . Infection and Immunity. Vol. 75 (5): 2136-2142

  19. Bhattacharjee, S., Majumder, N., Bhattacharyya, P., Bhattacharyya (Majumdar),S., and Majumdar, S. (2007)  Immunomodulatory role of arabinosylated   lipoarabinomannan on Leishmania donovani infected murine macrophages. Ind J. of Biochem & Biophys Vol. 44, 366-372

  20. Dey, R.,  Ghosh, S., Bhattacharjee, S.,  Majumder, N.,  and Majumdar, S. (2007). Ceramide as chief villain in the perspective of Visceral leishmaniasis:  Its role as the platform  for  pathogenic  establishment. Science and Culture. Vol. 73(5-6), 144-149 [Special issue on Current trends in Leishmania research]. Review.

  21. Dey, R., Majumder, N., Majumdar-Bhattacharyya, S.,  Bhattacharjee, S.,. Roychoudhury, K., Banerjee. S., Roy, S.  and Majumdar, S. (2007). Induction  of host protective Th1 immune response by chemokines in leishmania  donovani infected BALB/c mice.  Scan. J. Immunol. Vol. 66: 671-683

  22. Bhattacharjee, S., Dey, R., Bhattacharya, P., Mukherjee, A., Bhattacharyya (Majumdar), S. and Majumdar, S. (2007). Induction of host protective immune response by chemokines in visceral leishmaniasis: Importance of ceramide as a therapeutic target. Perspectives in Cytology and Genetics Vol 13: 115-124.

  23. Bhattacharyya (Majumdar), S., Dey, R., Majumder, N., Bhattacharjee, S  and Majumdar, S. (2008). A novel approach to regulate experimental visceral  leishmaniasis in murine macrophages using CCR5 siRNA. Scan. J. Immunol. Vol. 67: 345-353

  24. Majumdar, N., Bhattacharjee, S., Majumdar Bhattacharyya, S., Dey, R., Pal, N. K. and Majumdar, S. (2008). Restoration of impaired free radical generation and pro-inflammatory cytokines by MCP-1 in mycobacterial pathogenesis. Scan. J. Immunol  Vol. 67: 329-339.

  25. Majumdar, N., Bhattacharjee, S., Dey, R., Majumdar Bhattacharyya, S., Pal, N. and       Majumdar, S Arabinosylated lipoarabinomannan modulates the impaired cell    mediated immune response in Mycobacterium tuberculosis H37Rv infected C57 BL/6    mice (2008). Microbes and Infection.  Vol. 10(4), 349-357

  26. Sarkar, D., Saha, P., Gamre, S., Bhattacharjee, S., Hariharan, C., Ganguly, S., Sen, R.,         Mandal, G., Chattopadhyay, S., Majumder, S., Chatterjee, M. (2008). Anti-inflammatory effect of allylpyrocatechol in LPS-induced macrophages is mediated by suppression of iNOS and COX- 2 via the NF- κB pathway. Int. Immunopharmacol  Vol. 8: 1264-1271

  27. Kar Mahapatra, S., Das, S., Bhattacharjee, S., Gautam, N., Majumdar, S. & Roy, S. (2009). In vitro nicotine induced oxidative stress in mice peritoneal macrophages: a dose dependent approach. Toxicology Mechanisms And Methods  Vol. 19(2): 100-108

  28. Rub, A., Dey, R., Jadhav, M., Kamat, R., Chakkaramakkil, S., Majumdar,S.,  Mukhopadhyay, R., Saha. B. (2009). Cholesterol depletion associated with Leishmania major infection alters CD40  signalosome composition and effector function. Nature  Immunol.. Mar;10(3):273-80. Epub 2009 Feb 8.

  29. Maity, P.C., Bhattacharjee, S., Majumdar, S., and Sil, A.K. (2009). Potentiation of macrophage function by cigarette smoke against Leishmania donovani  infection. Inflammation Research. Vol.  58(1): 22-29

  30. 3Bhattacharjee, S., Gupta,G., Bhattacharya, P., Mukherjee, A., Majumdar Bhattacharyya,  S., Pal, A and Majumdar, S. (2009). Quassin alters the immunological patterns of murine macrophages through generation of nitric oxide to exert anti-leishmanial activitiy. J. Antimicrobial Chemotherapy.  Vol. 63(2): 317-324

  31. Bhattacharjee, S., Gupta,G., Bhattacharya, P., Adhikari, A.,  Majumdar Bhattacharyya,  S., and Majumdar, S. (2009). Anti-IL-10 MAb protection against experimental visceral leishmaniasis via induction of Th1 cytokines and nitric oxide. Ind. J. Expt. Biol Vol.47 : 489-497

  32. Gupta, G., Bhattacharjee, S., Bhattacharyya, S., Bhattacharya, P., Adhikari, A., Mukherjee, A., Majumdar Bhattacharyya, S  and Majumdar, S. (2009). CXC  chemokine mediated protection against  visceral leishmaniasis: Involvement of pro-inflammatory response. J. Infect. Dis.   Oct 15; 200(8):1300-10.

  33. Kar Mahapatra S, Chakraborty SP, Majumdar S, Braja Gopal Bag, Roy S. Eugenol protects nicotine-induced superoxide mediated oxidative damage in murine peritoneal macrophages in vitro. (2009). Eur J Pharmacol . Vol. 623. , 132-140.

  34. Gupta, G., Mukherjee A.K. and Majumdar. S. (2009). Mechanism of action of  Amphotericin B in Visceral Leishmaniasis. Perspectives in Cytology and Genetics. Vol. 14: 77-84. Review.

  35. Bhattacharya, P., Bhattacharjee, S., Gupta, G., Majumder, S., Adhikari, A., Mukherjee,   Asok., Bhattacharya Majumdar, S., Saha,  B & Majumdar, S. (2010). Ara-LAM Mediated  protection in visceral Leishmaniasis through upregulation of TLR-2 signaling: An  immunoprophylactic approach.  J. Infect. Dis. 2010 Jul 1;202(1):145-55.

  36. Mukherjee, A.K., Gupta, G., Bhattacharjee, S., Guha, S.K., Majumder, S., Adhikari, A., Bhattacharya, P., Majumdar Bhattacharyya, S., Majumdar, S. (2010). Amphotericin B regulates the host immune response in visceral leishmaniasis: Reciprocal regulation of protein kinase C isoforms. J. Infect.  Vol.61 (2) , 173-184

  37. Ashay Jain , Abhinav Agarwal, Saikat Majumder , Narendra Lariya, Anil   Khaya,  Himanshu Agrawal c, Subrata Majumdar b, Govind P. Agrawal (2010)   Mannosylated solid Lipid nanoparticles as vectors for site-specific delivery of an anti-cancer drug . J. Controlled Release . Vol. 20; 148 (3):, 359-67.

  38. Kar Mahapatra S, Bhattacharjee, S., Chakraborty SP, Majumdar S,  Roy S.  (2011).  Alteration of immune functions and Th1/Th2 cytokine balance in nicotine-induced  murine macrophages : Immunomodulatory role of eugenol and N-acetylcysteine Int. Immunopharmacol.  Vol. 11:  485-495

  39. Saha P, Bhattacharjee S, Sarkar A, Manna A, Majumdar S and Chatterjee M. (2011).    Berberine chloride mediates its anti-leishmanial activity via differential regulation of the   mitogen activated protein kinase pathway in macrophages. PLoS One.  Vol 6(4): e 18467

  40. Gupta G, Majumdar S, Adhikari A, Bhattacharya P, Mukherjee AK, Majumdar SB, Majumdar   S..,  (2011). Treatment with IP-10 induces host protective immune response  by  regulating the T regulatory cell functioning in Leishmania donovani infected mice Medical Microbiology and Immunology  May 1, Equipub, In Press.

  41. Bhattacharya P., Gupta G., Majumder S., Adhikari A.,  Banerjee Sayantan., Halder K., Bhattacharya Majumdar S., Ghosh M., Roy S and Majumdar S. et.al. (2011). Arabinosylated Lipoarabinomannan skews Th2 phenotype towards Th1 during Leishmania infection by chromatin modification: Involvement of MAPK signaling  PLoS One  In Press

       Publication Before joining at Bose Institute

  1. Majumdar, S., Das, S.K., Basu, S. and Bose, S.K. (1984). A note on   isolation of spontaneous glucose-resistant mutants of Bacillus subtilis. J.  Appl.  Bacteriol. 56 :    493.
  2. Majumdar, S., Das, S.K., Basu, S. and Bose, S.K. (1985). Initiation of sporulation of Bacillus subtilis by cyclic guanosine 3',5' monophosphate under condition of catabolite repression. Indian J. Biochem. Biophys. 22 : 259.
  3. Majumdar, S., Basu, S.  Das, S.K. and Bose, S.K. (1984). Studies on interrelationship between sporulation and synthesis of mycobacillin and dipicolinic acid under condition of catabolite repression in Bacillus subtilis. Folia Microbiol. 31 : 196.
  4. Majumdar, S. and Bose S. K. (1985). Derepression of sporulation and synthesis of mycobacillin and dipicolinic acidby cyclic guanosine 3'-5' monophosphate under conditions of glucose repression in Bacillus subtilis. J. Gen. Microbiol. 131: 2783.
  5. Das, S.K., Majumdar, S., Basu, S.,  Mukherjee S. and Bose, S.K. (1986). Selective action of mycobacillin on the cellular permeability of Aspergillus niger. J. Antibiotics. 39 : 581.
  6. Das, S.K., Basu, S., Majumdar, S. and Bose, S.K. (1986). Selective action of mycobacillin on the uptake of releasable materials by Aspergillus niger. Biochem. J. 239 : 317.
  7. Basu, S., Das, S.K., Majumdar, S., Bhattacharya, D. and Bose, S.K. (1986). Role of selective pressure by screening organisms in the development of producer revertants of different antibiotic markers. J. Appl. Bacteriol. 61 : 482.
  8. Basu, S., Das, S.K., Majumdar, S., and Bose, S.K. (1987). Multiplicity of antibiotic production from a strain of Aspergillus versicolor : versilin, a new and the third antifungal antibiotic. Indian J. Exp. Biol. 25 : 207.
  9. Mishra A.K., Roy, P., Roy Mahapatra, S.S., Mohanty, B. and Majumdar, S. (1986). Bioleaching of silica from magnesite ore. Indian J. technology. 24 : 770.
  10. Basu, S., Majumdar, S., Das, S.K. and Bose, S.K. (1987). Mutual and self-sensitivity among antibiotically active mutant derivatives from the inactive degenerate Aspergillus versicolor N5. J. Appl. Bacteriol. 63 : 53.
  11. Das, S.K., Mukherjee, S., Majumdar, S., Basu, S. and Bose, S.K. (1987). Physicochemical interaction of mycobacillin with Aspergillus niger protoplast membrane, the site of its action. J. Antibiotics. 40 : 1036.
  12. Bishayee, S., Majumdar, S., Scher, C.D. and Khan, S.( 1988).  Characterization of a novel anti-peptide antibody that recognizes a specific conformation of the platelet-derived growth factor receptor. Mol. Cell Biol. 8 : 3696.
  13. Bishayee, S., Majumdar, S.,  Khire, J. and Das, M. (1989). Ligand induced dimerization of PDGF-R. Monomer-dimer interconversion occurs independent of receptor.  Phosphoryaltion. J. Biol. Chem.  264:    11699.
  1. Majumdar, S., Rossi, M.W., Fujiki, T., Philips,  W.A., Disa, S., Qween, C.F., Johnston, R.B.Jr., Rosen, O.M., Corkey B.E. and Korchak, H.M. (1991). Protein kinase C isotypes and signaling in neutrophils . J. Biol. Chem. 266 : 9285.
  1. Kilpatrick, L., McCawley, L., nachiappan, V., Greer, W., Majumdar, S., Korchak, H. M.  and Douglas, S.D. (1992). Alpha-1 antichymotrypsin inhibits the NADPH oxidase enzyme complex in phorbol ester-stimulated  neutrophil membranes. J. Immunol.  149 : 3059.
  1. Majumdar, S., Kane L., Rossi, M.W., Volpp, B.B., Nauseef, W.M. and Korchak, H.M. (1993). Protein kinase C isotypes and signal transduction in human neutrophils : Neutrophil selective substrate specificity of Ca-dependent PKC and novel Ca-independent nPKC. Biochim. Biophys. Acta.  1176: 276.
  1. Bennet, M.J., Poirier, S.F., Chem, L., Gayton, A. R., Hosking, G. P., Le, N. A., Majumdar, S., and Korchak, S. (1993).  Juvnile neuronal ceroid lipofuscinosis: Characterization of the dyslipoproteinaemia and demonstration of membrane phospholipid and phospholipid-dependent signal transduction abnormalities in cultured skin fibroblasts. J. Inherit Metab Dis. 16(2): 308.
  1. Dyer, R.M., Majumdar, S., Douglas, S.D. and Korchak, H.M. (1994). Bovine parainfluenza 3 virus impairs superoxide anion generation and Calcium homeostasis in the bovine alveolar macrophage. J. Immunol. 153 (3) : 1171.

 

Patents:

 1.      Majumdar S, Majumder N. (2006). Arabinosylated Lipoarabinomannan as a      therapeutic tool against Tuberculosis and Leishmaniasis. Patent Application No.     772/KOL/2005, Govt. of India, International Classification No. A61K. 

2.      Majumdar S. (2006). A process for preparing pure Glycyrrhizic Acid from Licorice. Patent Application No. 771/KOL/2005, Govt. of India, International Classification No. A61K/31/00