Tapash Chandra Ghosh
Professor, Bioinformatics
PhD: Kalyani University  (1991)

Research interest

  • Molecular Evolution
  • Genome Analysis

 

Collaboraters:

  1. Dr. Shandar Ahamad (National Instistute of Biomedical Innovation, Japan)

Present Group Members

  1. Mrs Bratati Kahali (Senior Research Fellow)
  2. Miss Tina Begum (Senior Research Fellow)
  3. Miss Soumita Podder (Senior Research Fellow)
  4. Miss Tanusree Bhattacharya (Junior Research Fellow)
  5. Mrs Kamalika Sen (Junior Research Fellow)
  6. Mr Sandip Chakrabarti (Junior Research Fellow)
  7. Mr. Sanjib Kumar Gupta (Technical Assistant)
  8. Mr. Tushar Kanti Bhattacharya (Technical Officer)
  9. Mrs Sujata Roy (Technical Assistant)

 Important publications : 

(1)   Podder, S and T.C. Ghosh. 2010. Exploring the differences in evolutionary rates between monogenic and polygenic disease genes in human. Mol Biol Evol. 27:934- 941. 

(2)   Begum, T and T.C. Ghosh 2010. Understanding the Effect of Secondary Structures and Aggregation on Human Protein Folding Class Evolution. J Mol Evol. (in press) 

(3) Manna B., T. Bhattacharya, B. Kahali and T. C. Ghosh 2009 Evolutionary constraints on hub and non-hub proteins in human protein interaction network: insight from protein connectivity and intrinsic disorder. Gene 434: 50-55. 

(4) Podder, S., P. Mukhopadhyay and T. C. Ghosh. 2009. Multifunctionality dominantly determines the rate of human housekeeping and tissue specific interacting protein evolution. Gene 439: 11-16. 

(5)   Mukhopadhyay, P.,  S. Basak and T. C. Ghosh. 2008. Differential Selective Constraints Shaping Codon Usage Pattern of Housekeeping and Tissue Specific Homologous Genes of rice and Arabidopsis. 2008. DNA Research 15: 347-356.  

(6)   Basak, S., S. Roy, and T.C. Ghosh. 2007. On the origin of synonymous codon usage divergence between thermophilic and mesophilic prokaryotes. FEBS Letters 581: 5825-5830.  

(7)   Mukhopadhyay, P.,  S. Basak, and T. C. Ghosh. 2007. Nature of selective constraints on synonymous codon usage of rice differs in GC-poor and GC-rich genes. Gene 400: 71-81. 

(8) Basak, S., and T.C. Ghosh 2006. .Temperature Adaptation of Synonymous Codon Usage in Different Functional Categories of Genes: A Comparative Study betweenMethanococcus jannaschii and Methanococcus maripaludis Homologous Genes. FEBS Letters 580: 3895-3899. 

(9) D’Onofrio, G., T.C. Ghosh and G. Bernardi. 2002. The base composition of the human genes is correlated with the secondary  structures of the encoded proteins.  Gene 300:179-187.  

(10)      Gupta, S.K., S. Majumdar, T.K. Bhattacharya, and T.C. Ghosh. 2000. Studies on the relationships between the synonymous codon usage and protein secondary  structural units. Biochem Biophys Res Commun. 269: 692-696.

 

 Full list of publications

 

Contact

tapash@bic.boseinst.ernet.in